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Recordings will be made before, during, and after an acute episode of Congestive Heart Failure (CHF). The recording protocol will be comprised of: 1) sustained vowels, 2) standard sentences and a reading passage, and 3) 30 seconds of spontaneous speech. The ACC is easily placed on the anterior neck just above the clavicular notch using double-sided medical grade adhesive tape (see Figure 1). The ACC is relatively immune to environmental noise, and we have been able to extract some voice quality-related measures from the ACC signal. For this reason it is proposed that recordings of voice/speech production for this pilot study be obtained simultaneously with both a microphone and a neck-placed miniature accelerometer (ACC). The types of analyses that can be performed on the airborne acoustic (microphone) signal are somewhat limited by the levels of background noise in the recording environment, particularly with respect to some of the acoustic measures related to voice quality. The establishment of the underlying etiology of the heart failure will help determine how it may contribute to symptomology and changes in acoustic and accelerometric measures of voice and speech production. The primary endpoint is significant correlation of changes in voice and speech characteristics with change in total body water as measured by change in weight during the hospital admission.Ģ.3 Measurement Precision Exploratory endpoints will be to determine the distributions of lung fluid values for patients with confirmed acute heart failure syndrome and to determine if acoustic and accelerometer-based measurements have sufficient sensitivity to detect changes in lung fluid status in a symptomatic hospitalized population. A blinded observational methodology was chosen as the most appropriate study design to understand changes in lung fluid values in patients with acute heart failure syndrome with pulmonary congestion. Changes in lung fluid in acute heart failure syndrome are difficult to diagnose and evaluate.
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Up to 12 subjects will be enrolled to comparatively evaluate the voice outcome measures in this pilot study. Results of this study will evaluate the sensitivity of voice and speech measures in detecting changes in lung fluid status in a symptomatic population. Patients admitted for acute heart failure syndrome with pulmonary congestion with an expected stay greater than 3 to 4 days, who are willing and able to sign an informed consent, and who meet all inclusion/exclusion criteria, as identified by the clinical investigator, will be enrolled in the study. The study shall be conducted in concordance with the United States FDA regulations for a non-significant risk study. This is an observational, single center study to evaluate if acoustic and accelerometer-based measures of voice and speech have sufficient precision to detect a change in lung fluid status for patients with confirmed acute heart failure syndrome with pulmonary congestion. Why Should I Register and Submit Results?.It's like not having any engine oil in your car. If you are also not using your voice properly, so that it is already under strain, then speaking with dry vocal cords for extended periods of time is likely to cause injury. Like any other soft tissues, the vocal cords should be moist but are likely to become dehydrated. Caffeine is a diuretic, encouraging the discharge of liquids from the body. Voice specialists agree that drinking tea and coffee all day can have a damaging effect on vocal cords. the appearance of vocal nodules, tumours or ulcers and.In more severe cases, vocal strain can produce: the voice becoming harsh, raspy, shrill or thin.the urge to cough or clear the throat and.tension, leading to change in voice quality.pain, leading indirectly to a change in voice tone or quality.Voice strain can be revealed by the following early symptoms:
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Voice damage means more than just losing your voice.